Metabolism Alprazolam is extensively metabolized in people, mostly by cytochrome P450 3A4 (CYP3A4), to 2 major Lively metabolites during the plasma: four-hydroxyalprazolam and ?-hydroxyalprazolam. The plasma circulation levels of The 2 Lively metabolites are a lot less than 4% from the mother or father. The claimed relative potencies in benzodiazep